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Comparision of safety of levobupivacaine and ropivacaine for spinal anaesthesia in caeserian section

Safety and efficacy of intrathecal heavy 0.5% bupivacaine and 0.75% ropivacaine in elective ceserian section patients:A randomized double blinded controlled study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/09/057887
Enrollment
76
Registered
2023-09-20
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O80- Encounter for full-term uncomplicated delivery

Interventions

Intervention1: Levobupivacaine ans ropivacaine given in subarachnoid space: In 1 group 0.5% levobupivacaine and 20 microgram fentanyl total 2.2 volume in subarachnoid space In other group 0.75% ropiv

Sponsors

Geetanjali medical college and hospital
Lead Sponsor
Department of anaesthesia geetanjali medical college and hospital
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: ASA GRADE 2 full term caeserian section above 37 weeks gestation Uncomplicated pregnancy

Exclusion criteria

Exclusion criteria: Patient refusing spinal anaesthesia Spinal deformity Pregnancy induced hypertension Hypersensitivity to local anaesthetic drug Coagulation abnormality

Design outcomes

Primary

MeasureTime frame
To compare motor & sensory blockade between two groupsTimepoint: Motor blockade assessed by modified bromage sclae Every 1 minute till 5 minutes after spinal anaesthesia then every 2 minutes till 20 minutes , untill end of surgery Sensory effect assessed every 1 minute till 5 minutes after spinal anaesthessi then every 2 minute upto 20 minutes untill the end of surgery

Secondary

MeasureTime frame
Postoperative analgesia by using Visual Analogue Scores (VAS) -Rescue analgesia required in postoperative period - Haemodynamic variables -Intraoperative & postoperative side effects Timepoint: Perioperative maternal hypotension or episodes of bradycardia respiratory depression, nausea, vomiting & pruritus will be recorded. Newborns will be evaluated with APGAR score at 1min & 5 min. During the procedure, the surgeons evaluated muscle relaxation according to a four-point scale Pain will be assessed with a 10-cm linear visual analogue scale (VAS) at incision, birth and peritoneal closure and at15 min intervals after surgery

Countries

India

Contacts

Public ContactPooja Patel

Geetanjali medical college and hospital

poojaptl.14@gmail.com9586557712

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026