Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sevoflurane: Sevoflurane concentration (%w/v) will be adjusted to maintain target entropy value of 70 during cardiopulmonary bypass.
Control Intervention1: Standard institutional protoc
Sponsors
Armed Forces Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1.Elective paediatric patients (0-14 years) undergoing cardiac surgery on CPB.2.Written informed consent.
Exclusion criteria
Exclusion criteria: 1.An active infection with temperature 38.0C 2.History of a neurological disease 3.Previously diagnosed with renal and hepatic disorder 4.Emergency surgery 5.Any kind of diagnosed or suspected syndrome 6.Deep hypothermic circulatory arrest
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in sevoflurane end oxygenator concentration with entorpy-guided sevoflurane administration.Timepoint: At the time of induction At the time of skin incision At the time of sternotomy At the time of starting of CPB At the time of cross clamping of Aorta At 10 minutes intervals during CPB At the time of removal of cross clamp from Aorta At the time of stopping CPB At the time of skin closure | — |
Secondary
| Measure | Time frame |
|---|---|
| IBP MAP CPB flow Sevoflurane dial concentration (% w/v) Body Temperature ETCO2 FiO2 VIS Timepoint: At 10 minutes intervals during CPB | — |
Countries
India
Contacts
Public ContactDR RAHUL YADAV
Army Institute for Cardiothoracic Sciences
Outcome results
None listed