Study of injection methylene blue after surgery around anus for decreasing pain

To evaluate the use of injection methylene blue in post operative perianal surgery for pain relief - Nil

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057852

Enrollment

Registered

2023-09-19

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: INJ METHYLENE BLUE: Subdermal injection of 0.5 mg/kg of MB per point in 4 points (upper, lower, left, and right), adjacent to the surgical incision in perianal area to be given after

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing perianal surgery,who are willing to participate in the study and will give written informed consent.

Exclusion criteria

Exclusion criteria: 1)Patient allergic to methylene blue. 2)Patients with immune compromised status. 3)Patients on anticoagulant therapy. 4)Patients who underwent repeated perianal surgery. 5)Patients with skin infection (fungal infections etc). 6)Diabetes mellitus, neuropathy, trauma,

Design outcomes

Primary

Measure	Time frame
To assess use of pain relief of Methylene blue by assessing pain score on visual analogue scale (VAS scale)at 4,8,12,24 hours interval for 5 days postoperativelyTimepoint: At 4,8,12,24 hours interval for 5 days post operatively	—

Secondary

Measure	Time frame
Secondary outcomes will be noted like skin edema, Staining of skin, Local pain, Dizziness, fever, redness, local rise in temperature etcTimepoint: At 4,8,12,24 hours interval for 5 days post operatively	—

Countries

India

Contacts

Public ContactDr Rajendra Shinde

M.G.M Medical College and Hospital,

prj95au@gmail.com8169230538

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026