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Medical management of osteoarthritis knee pain using interventional nerve block

Genicular nerve radiofrequency ablation for chronic knee osteoarthritis pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/09/057832
Enrollment
100
Registered
2023-09-19
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Genicular Nerve Block: Bupivacaine (2 mL of 0.25%) and triamcinolone (40mg) will be injected before activation of the RF generator (Cosman, Burlington, USA). The RF electrode is then in

Sponsors

Sir Ganga Ram Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) OA- related chronic knee pain for = 6 months 2) Radiologic tibiofemoral OA (grade 2-4, Kellgren Lawrence grading for OA knee, evaluated by an experienced radiologist)

Exclusion criteria

Exclusion criteria: 1) Prior knee surgery 2) Serious neurologic or psychiatric disorder 3) Injection with steroids or hyaluronic acid during the previous 3 months 4) Current use of anticoagulant drugs 5) Patients who refuse a single staged procedure

Design outcomes

Primary

MeasureTime frame
Effective pain relief (at least 50% reduction in VAS pain score from baseline) by a single setting therapeutic blockTimepoint: 1week, 4 weeks, 12 weeks and 24 weeks

Secondary

MeasureTime frame
Effects of knee function and quality of life (Oxford knee score) and requirements of adjuvant analgesia Timepoint: 1week, 4 weeks, 12 weeks and 24 weeks follow-up period

Countries

India

Contacts

Public ContactDr Naresh Dua

Sir Ganga Ram Hospital

ndua14@yahoo.com9313097996

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026