FindTrial
Sign In

Platelet Rich Plasma (PRP) treatment for knee osteoarthritis

Assessment of MRI guided changes on articular cartilages after intra-articular injection of Platelet Rich Plasma (PRP) in knee osteoarthritis - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/09/057803
Enrollment
234
Registered
2023-09-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: nil: nil

Sponsors

Principal, R G Kar Medical College Hospital
Lead Sponsor
Blood bank MRI unit R G Kar Medical College Kolkata
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients of both sex and age group of 45-65 years, coming to Pain OPD with history of pain for the last 3 months according to the American College of Rheumatology (ACR) criteria for knee osteoarthritis along with radiologic evidence of joint destruction based on Kellgren-Lawrence criteria (including grades 1, 2, and 3)

Exclusion criteria

Exclusion criteria: 1) any contraindication to do MRI including pacemakers, aneurism clips, claustrophobia, non-MRI compatible metallic devices in the body. 2) viscosupplements, ozone, corticosteroid etc. injection at knee joint in the preceding 3 months. 3) any kind of knee or other surgery in the past 6 months. 4) having autoimmune disease, collagen vascular disease. 5) history of cancer and immunodeficiency state. 6) active infection or inflamed or traumatic lesion in the knee. 7) platelet disorder, low platelet count (less than 150,000/microliter) and blood dyscrasias. 8) intake of anticoagulant or anti-platelet drugs within 10 days of injection. 9) intake of NSAIDs group of drugs within 5 days of injection. 10) intake of systemic corticosteroids within 2 weeks of the injection. 11) pregnancy and lactation. 16) any kind of knee joint deformities like genu valgum or genu varum more than 20 degrees.

Design outcomes

Primary

MeasureTime frame
Changes of knee articular cartilage thickness of knee joint after PRP treatment in knee osteoarthritisTimepoint: 5 month—

Secondary

MeasureTime frame
Changes of physical findings or signs as pain, stiffness, movement of knee joint after prp treatment in knee osteoarthritisTimepoint: 5 months—

Countries

India

Contacts

Public ContactDr Debdipta Das

R G KAR Medical College Kolkata, Department of Anesthesiology and Pain

drdebdiptadas@gmail.com9163621292

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026