Comparison of two intravenous drugs (Magnesium Sulphate and Fentanyl) for passing tube (Endotracheal tube) via nose with help of fiber scope in awake patients

Comparison Between IV Magnesium Sulphate and IV Fentanyl on Intubating Conditions During Awake Fibreoptic Intubation: A Prospective Randomised Double Blind Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057778

Enrollment

Registered

2023-09-18

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H720- Central perforation of tympanic membrane Health Condition 2: H712- Cholesteatoma of mastoid Health Condition 3: H701- Chronic mastoiditis Health Condition 4: S024- Fracture of malar, maxillary and zygoma bones Health Condition 5: S026- Fracture of mandible Health Condition 6: C01- Malignant neoplasm of base of tongue Health Condition 7: C021- Malignant neoplasm of border of tongue Health Condition 8: C73- Malignant neoplasm of thyroid gland Health Condition 9: C502- Mal

Interventions

Intervention1: AWAKE FIBREOPTIC INTUBATION: Comparison Between IV Magnesium Sulphate (45milligram/kg) and IV Fentanyl (2microgram/kg) on Intubating Conditions During Awake Fibreoptic Intubation Contro

Eligibility

Inclusion criteria

Inclusion criteria: Patients with ASA physical status Grade I and II Patients undergoing elective surgery under general endotracheal anaesthesia Patients with Mallampati Class I and II

Exclusion criteria

Exclusion criteria: Patient refusal Psychiatric patients Emergency surgery Patients with severe bradycardia/heart block Pregnant and lactating mothers Patients having known allergy to any drugs used in the study Patients on long term opioids or sedative medication Patient contraindicated to nasal intubation such as grossly distorted anatomy, URTI, and bleeding disorders

Design outcomes

Primary

Measure	Time frame
Cough score (severity of cough) during awake fibreoptic intubationTimepoint: During awake fibreoptic intubation (2 min)	—

Secondary

Measure	Time frame
Intubating conditions Ramsay sedation score Hemodynamic parameters Side effect/Complications if anyTimepoint: Upto 24-hour post operatively	—

Countries

India

Contacts

Public ContactDr Prakriti singh

R.N.T Medical College

sharma0979@yahoo.co.in09214323557

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026