Health Condition 1: G061- Intraspinal abscess and granuloma
Conditions
Interventions
Intervention1: Brain relaxation score will be assessed by the operating surgeon immediately on opening the duramater on a four-point scale: 24hrs -48hrs
Control Intervention1: hospital and neurologica
Sponsors
Department of Neurosurgery
Eligibility
Inclusion criteria
Inclusion criteria: Patient of either sex, Age group of 18-60 years ASA Grade I and II Elective Supratentorial Craniotomy
Exclusion criteria
Exclusion criteria: Patient refusal Hyponatremia or Hypernatremia (Serum Na 150 mEq/L) Pregnancy Cardiac dysfunction with dysrhythmia Renal dysfunction History of recent craniotomy/Head injury ( Active psychiatric or neurological disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| •To compare the effect of equimolar 3% Hypertonic Saline, 8.4 % Sodium Bicarbonate & 20% mannitol on intracranial pressure (ICP).Timepoint: 48 hrs to 72 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the following parameters between the groups: Cerebral perfusion pressure (CPP), Brain relaxation, Metabolic changes (ABG, Serum Osmolarity) & electrolytes, Hemodynamic parameters Heart Rate (HR), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Mean Arterial Pressure (MAP), Central Venous Pressure (CVP). The neurological outcome at the time of discharge of patient from the hospital (Extended Glasgow Outcome Scale (GOS-E), Complications if any like Hypotension, hyponatremia, hypernatremia, hyperkalemia, hypokalaemiaTimepoint: at the time of surgery | — |
Countries
India
Contacts
Public ContactPROF B B KUSHWAHA
King Georges Medical University Lucknow
Outcome results
None listed