The study the effect of intranasal and intravenous dexmeditomidine

Comparative study of intranasal and intravenous dexmeditomidine for attenuation of haemodynamic responses to laryngoscopy and endotracheal intubation in adult surgical patients under general anaesthesia

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057760

Enrollment

100

Registered

2023-09-18

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intravenous Dexmeditomidine: Administration of intravenous dexmeditomidine for attenuation of haemodynamic responces to laryngoscopy and endotracheal intubation in adult surgical patien

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adult patients belonging to ASA grade I &II 2.Scheduled for elecytive surgery under general anaestheia.

Exclusion criteria

Exclusion criteria: 1. Uncooperating, non consenting patients. 2. Known allery or hypersenstivity to dexmeditomidine. 3. Pregnant, lactating mothers, Cardiac or respratory disease, uncontrolled hypertension, diabetes mellitus type II, neurological or psychiatric disease, or any intranasal pathology{like nasal ulcers, polyps, nasaal septal deviation}.

Design outcomes

Primary

Measure	Time frame
Mean arterial pressure{MAP}Timepoint: 40 minutes before induction, 2 min before induction, 2,5,7,9 min after induction.	—

Secondary

Measure	Time frame
Systolic blood pressure{SBP}, diastolic blood pressure{DBP} & heart rate.Timepoint: 40 minutes before induction, 2 min before induction, 2,5,7,9 min after induction.	—

Countries

India

Contacts

Public ContactDr. Rajpal Singh

Vardhman Mahavir Medical College and Safdarjung Hospital, Ansari Nagar East, New Delhi-110029

doctorrajpal04@gmail.com9811858311

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026