To compare nebulized magnesium sulphate with nebulized lignocaine in attenuating pressor response to laryngoscopy and intubation in patients undergoing general anaesthesia

A prospective randomized study to compare nebulized magnesium sulphate with nebulized lignocaine in attenuating pressor response to laryngoscopy and intubation in patients undergoing general anaesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057750

Enrollment

Registered

2023-09-15

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: A prospective randomized study to compare nebulized magnesium sulphate with nebulized lignocaine in attenuating pressor response to laryngoscopy and intubation in patients undergoing ge

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I and II patients of either sex in age group of 18-60 years posted for surgery under general anaesthesia, who are either sex and willing to participate will be included in this study.

Exclusion criteria

Exclusion criteria: patients with refusal of consent, history of hypertension, patients having cardiovascular dysfunction, epilepsy, pregnancy, anticipated difficult airway, patients with known history of allergy to study drug.

Design outcomes

Primary

Measure	Time frame
TO ASSESS EFFICACY OF NEBULIZED MAGNESIUM SULPHATE IN COMPARISON TO NEBULIZED LIGNOCAINE ON HYPERTENSIVE TACHYCARDIA RESPONSE TO LARYNGOSCOPY ANMD INTUBATION DURING GENERAL ANAESTHESIATimepoint: AFTER INTUBATION 1MIN,3MIN,5MIN	—

Secondary

Measure	Time frame
TO EVALUATE SIDE EFFECTS ASSOCIATED WITH USE OF THESE DRUG,IF ANY1.HYPOTENSION 2.BRADYCARDIA 3. FALL IN SATURATION 4.ANY OTHERTimepoint: WITHIN 30 MIN	—

Countries

India

Contacts

Public ContactDR MOHIT

DEPARTMENT OF ANAESTHESIOLOGY AND CRITICSAL CARE,PT.B.D.SHARMA,PGIMS ROHTAK

mohithalder28@gmail.com9034133070

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026