A comparative study to evaluate the effect of 5% Eutectic mixture of local anaesthesia(EMLA) cream vs lubricating gel on postoperative sore throat in adults following endotracheal intubation in surgeries performed under general anaesthesia

An interventional randomized comparative study to evaluate the effect of 5% EMLA cream vs lubricating gel on postoperative sore throat in adults following endotracheal intubation under general anaesthesia in Department of Anaesthesia SMS Medical college, Jaipur - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057745

Enrollment

Registered

2023-09-15

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 5%EMLA cream: role of 5% Eutetic mixture of local anaesthesia (EMLA) cream applied on cuff of endotracheal tube in preventing post op sore throat in patient undergoing tracheal intuba

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients scheduled for elective surgeries 2.Expected duration of surgery around 2 to 3 hours under general endotracheal anaesthesia 3.Patients belonging to American Society Of Anaesthesiologists (ASA) grade I, II

Exclusion criteria

Exclusion criteria: 1.Patients allergic to local anaesthetics 2. >2 intubation attempts, assisted nasogastric tube insertion, difficult airway 3.Patients with head and neck surgery involving airway 4.Patients with preoperative sore throat 5.Expected prolonged surgical duration ( >3 hours) 6.Postoperative mechanical ventilation 7.Surgeries in prone position

Design outcomes

Primary

Measure	Time frame
1 incidence of postoperative sore throat(POST) 2 severity of POST 3 incidence and severity of post-operative cough 4 Incidence and severity of post-operative hoarseness of voiceTimepoint: immediately after the surgery 2 hours post operatively 6 hours post operatively 12 hours post operatively 24 hours post operatively	—

Secondary

Measure	Time frame
N/ATimepoint: N/A	—

Countries

India

Contacts

Public ContactRohan Garg

Sawai Man Singh medical college, Jaipur

mdhaka81@gmail.com8696909181

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026