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Comparison of influence of three types of fluids on kidney function of children admitted with low blood pressures

Comparison of effect of balanced crystalloid, unbalanced crystalloid and colloid on incidence of AKI in children with hypotensive shock: An open randomized control trial. - NILL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/09/057723
Enrollment
99
Registered
2023-09-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I959- Hypotension, unspecified

Interventions

Intervention1: Balanced crystalloid ( Physiomax) Intravenous fluid Bolus: Fluid bolus of 5-10 milli litre per kilogram body weight and repeated as needed for treating hypotension. Maximum of 40 milli

Sponsors

Rainbow children hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients who present to our hospital with features of hypotensive shock shall be included in the study from 1 month age till 18 years age.

Exclusion criteria

Exclusion criteria: Children with chronic kidney disease Children with traumatic brain injury. Immediate Post-surgical patients within 24 hours of surgery.

Design outcomes

Primary

MeasureTime frame
Incidence of primary or progressive acute kidney injury amongst three intervention groups at the end of fourty eight hours of presentationTimepoint: fourty eight hours after presentation

Secondary

MeasureTime frame
Change in SOFA (Sequential organ failure assessment) score over 48 hoursTimepoint: After 48 hours of presentation;To compare the incidence of Hyperchloremia & associated acidosisTimepoint: After 48 hours of presentation;To compare the need for RRT (Renal replacement therapy).Timepoint: After 48 hours of presentation;To evaluate & compare the time taken for resolution of shock amongst the three groupsTimepoint: Till the shock has resolved

Countries

India

Contacts

Public ContactDr B Pavan Kumar

Rainbow children hospital

ksachane@yahoo.com9112406452

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026