To compare the use of lignocaine and dexmedetomidine together versus lignocaine alone to nebulize patients with predicted difficult airway for awake fibreoptic nasal intubation

Comparison of intubating conditions with combined lignocaine and dexmedetomidine nebulization versus lignocaine alone for awake fiberoptic-guided nasotracheal intubation in patients with anticipated difficult airway - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057719

Enrollment

Registered

2023-09-15

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: J398- Other specified diseases of upperrespiratory tract

Interventions

Intervention1: Dexmedetomidine and lignocaine: Nebulization with 4ml 4% lignocaine and 1mcg/kg dexmedetomidine for 20 minutes Control Intervention1: Plain lignocaine: Nebulization with 4ml of 4% ligno

Eligibility

Inclusion criteria

Inclusion criteria: patients aged 18-65 years, belonging to American society of Anaesthesiologists (ASA) physical status I-II with anticipated difficult airway and planned to undergo nasotracheal intubation

Exclusion criteria

Exclusion criteria: 1. Allergy to local anaesthetics. 2. Significant systemic co-morbidities. 3. Glottic or sub-glottic obstruction.

Design outcomes

Primary

Measure	Time frame
Cough scoreTimepoint: From the time FOB is inserted in nostril until intubation is accomplished which is the intubation time	—

Secondary

Measure	Time frame
Intubation timeTimepoint: Intubation time will be defined as time from insertion of fibreoptic bronchoscope in the nostril till the appearance of capongram (EtCO2) on the monitor;Patient comfort score & operator satisfaction scoreTimepoint: During intubation time;Supplemental dose of midazolam & local anaesthetic (Spray As You GO)Timepoint: During intubation time;Vocal cord positionTimepoint: During intubation time	—

Measure

Time frame

Intubation timeTimepoint: Intubation time will be defined as time from insertion of fibreoptic bronchoscope in the nostril till the appearance of capongram (EtCO2) on the monitor;Patient comfort score & operator satisfaction scoreTimepoint: During intubation time;Supplemental dose of midazolam & local anaesthetic (Spray As You GO)Timepoint: During intubation time;Vocal cord positionTimepoint: During intubation time

—

Countries

India

Contacts

Public ContactDr Suman Saini

Vardhman mahavir medical college and safdarjung hospital

drsainisumannony@gmail.com9891228793

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026