A clinical trial to study the effect of two drugs etomidate and propofol in patients with psychiatric illness undergoing electroconvulsive therapy

A randomized double blinded control trial to compare the effect of intravenous etomidate vs propofol on haemodynamic responses and seizure duration during modified electroconvulsive therapy - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057699

Enrollment

Registered

2023-09-15

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F30-F39- Mood [affective] disorders

Interventions

Intervention1: ETOMIDATE: 0.2mg/kg intravenous dose for 15 months Control Intervention1: propofol: 1mg/kg intravenous dose for 15 months

Eligibility

Inclusion criteria

Inclusion criteria: 1 ASA I and II

Exclusion criteria

Exclusion criteria: 1 Known allergy to the studying drug 2 Patients having neuromuscular disorders,cardiovascular diseases and epilepsy 3 pregnancy 4 Major sickness like sevre bronchial asthma 5 patient refusal

Design outcomes

Primary

Measure	Time frame
haemodynamic responses includes changes in heart rate,mean arterial pressure,systolic blood pressure,rate pressure productTimepoint: 15 months	—

Secondary

Measure	Time frame
seizure durationTimepoint: 15 months;adverse effects between etomidate & propofolTimepoint: 15 months	—

Countries

India

Contacts

Public ContactASIF MAMMUTTY P M

KMCT MEDICAL COLLEGE,KOZHIKODE

asifmammuttypm@gmail.com8129632088

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026