Health Condition 1: L814- Other melanin hyperpigmentation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age over 18 years Clinical diagnosis of extra-facial melasma characterized by the presence of brownish hyperpigmented spots under regular illumination, with irregular borders, symmetrically distributed in body areas except the face.
Exclusion criteria
Exclusion criteria: 1 History of post-inflammatory hyperpigmentation and hyperchromic contact dermatitis with symptoms such as itching, stinging, burning, or local trauma before the appearance of the lesions. 2 Pregnant women 3 Patients with contraindications for skin biopsy such as a history of keloid formation or coagulation disorders 4. Patients not giving consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To compare pathogenic mechanisms of facial and extrafacial melasma on immunohistochemical analysisTimepoint: at 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| 2. To study the immunohistochemistry in extrafacial melasmaTimepoint: 1 year | — |
Countries
India
Contacts
AIIMS BILASPUR