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The effectiveness of intravenous calcium chloride in addition to oxytocin versus oxytocin alone in minimizing blood loss during birth by cesarean section.

Efficacy of intravenous calcium chloride plus oxytocin vs oxytocin alone for the prevention of blood loss during caesarean delivery: A randomized controlled trial. - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/09/057657
Enrollment
100
Registered
2023-09-14
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group A: After fetal delivery, all patients will receive 1 gram of calcium chloride in 100 mL of sterile saline over the course of 15 minutes. Patients will continue to receive all stan

Sponsors

All India Institute of Medical Sciences Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant patients undergoing caesarean section in spinal anaesthesia will be included in the study. - Patients in labor. - Patients receiving an oxytocin infusion for labor augmentation prior to caesarean. - Uncomplicated, singleton pregnancy - ASA class 1 & 2.

Exclusion criteria

Exclusion criteria: - Patients with multiple pregnancies - Complicated pregnancies - Underlying cardiac condition or history of arrhythmia. - Contraindication to spinal anaesthesia.

Design outcomes

Primary

MeasureTime frame
To measure the total estimated blood loss (EBL) in intraoperative period after the intravenous calcium chloride and 7.5U/h oxytocin infusion and 7.5 U/h of oxytocin alone during caesarean section under spinal anaesthesia.Timepoint: Intraoperative period

Secondary

MeasureTime frame
- Adequacy of uterine tone. - Need for additional uterotonics. - Incidence of postpartum haemorrhage (PPH). - Any calcium chloride-related side effects for example: arrhythmia, bradycardia, hypotension, nausea, vomiting, chest pain. Timepoint: Intraaoperative period

Countries

India

Contacts

Public ContactKunal Singh

All India Institute of Medical Sciences Patna

drsinghkunal@gmail.com9411514945

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026