Comparison of 2 drug combination for providing adequate sleep in medical gastrology procedures

A COMPARATIVE STUDY OF KETAMINE-DEXMEDETOMIDINE WITH KETAMINE-PROPOFOL FOR SEDATION DURING ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057650

Enrollment

Registered

2023-09-14

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere

Interventions

Intervention1: ketamine- dexmedetomidine for sedation during ERCP: Patient will receive an IV loading dose of 1 mg/kg ketamine and 0.5 mcg/kg of dexmedetomidine over 10 minutes as an infusion, followe

Eligibility

Inclusion criteria

Inclusion criteria: BMI ASA physical status 1 and 2

Exclusion criteria

Exclusion criteria: Patients on adrenergic blocking drugs , calcium channel blockers Patients with cardiac arrhythmias , CCF and heart blocks Patients with H/O alcohol , opioid , sedative drug abuse

Design outcomes

Primary

Measure	Time frame
time taken to achieve Ramsay sedation score of 3 to 4 and MMSE score of 25Timepoint: 5 minutes	—

Secondary

Measure	Time frame
procedural recall by modified Brice questionnaireTimepoint: 24 hours	—

Countries

India

Contacts

Public ContactRenuka R

Sapthagiri institute of medical sciences and research centre

drmadhumitha99@gmail.com9972478051

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026