Health Condition 1: M50-M54- Other dorsopathies
Conditions
Interventions
Intervention1: intervention is by using injection ketamine (at rate 0.5mg/kg bolus thereafter 0.25mg/kg/hr till end of surgery) versus inj lidocaine( at 1.5mg/kg bolus and thereafter at rate 1.5mg/kg/
Sponsors
Armed Forces Medical College
Eligibility
Inclusion criteria
Inclusion criteria: a)ASA Physical Status 1 and 2 (American Society of Anaesthesiologists physical status grading classification) b)Scheduled to undergo posterior decompression surgery for PIVD, c)Planned to undergo the surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: a)History of allergic/adverse reaction to study medications (ketamine or lidocaine), b)Patients with severe cardiac, hepatic, and renal disease, c)Patients with long-term opioid and nonopioid analgesic use, d)Pregnant patients (with any duration of gestation), e)Patients unable to communicate independently during the preoperative evaluation, f)Patients with any history of psychiatric illness (with or without present medications/therapy), g)Patients with a history of stroke, head injury, and intracranial mass/bleeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)To compare the effect of intraoperative ketamine & lidocaine infusion on Mobility evaluated by 6MWD,On Post operative day 2. 2)Length of hospital stay (In Days)Timepoint: 1)To compare the effect of intraoperative ketamine & lidocaine infusion on Mobility evaluated by 6MWD, On Post operative day 2. 2)Length of hospital stay (In Days) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) VAS score at 6th hour post operatively. 2)Intraoperative hemodynamic variation. 3)incidence of icu admission.Timepoint: 6 hour | — |
Countries
India
Contacts
Public ContactDr J John Magesh kumar
Armed Forces Medical College,Pune
Outcome results
None listed