Health Condition 1: O722- Delayed and secondary postpartum hemorrhage
Conditions
Interventions
Intervention1: Administration of carbetocin: Carbetocin would be administered in a standard manner. 100 ug Carbetocin bolus would be administered intravenously. Prior to spinal anesthesia, the women w
Sponsors
Datta Meghe Institute of Higher Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Consenting, healthy pregnant women, with singleton pregnancy, undergoing elective caesarean section at term with regional anesthesia.
Exclusion criteria
Exclusion criteria: Women with placenta previa, placental abruption, and multiple gestation as these conditions are associated with an increased risk of PPH. Women with pregnancy-related complications and disorders such as pre-eclampsia, gestational diabetes, or pre-existing diseases such as insulin-dependent diabetes, cardiovascular or renal diseases, or hypo-/hyperthyroidism (these conditions could possibly interfere with hemodynamic parameters). Women taking medication with a known impact on the cardiovascular system. Women undergoing caesarean section with general anesthesia were also excluded, as carbetocin is licensed for use only with regional anesthesia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effects of both drugs on maternal heart rate (HR) and blood pressure (BP).Timepoint: 1 hour (starting from drug administration till one hour thereon). | — |
Secondary
| Measure | Time frame |
|---|---|
| The impact of both drugs on post operative blood loss, and need of additional uterotonics, and changes in post operative hemoglobin and uterine tone.Timepoint: Post operative 1 hour | — |
Countries
India
Contacts
Public ContactDr Surekha Tayade
Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research
Outcome results
None listed