Effectiveness of Salbutamol in treatment of TTNB- A RCT STUDY

A randomized controlled trial of the efficacy of inhaled salbutamol with standard therapy vs standard therapy alone for treatment of transient tachypnoea of newborn TTNB - NOT APPLICABLE

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057567

Enrollment

100

Registered

2023-09-13

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J80- Acute respiratory distress syndrome

Interventions

Intervention1: Salbutamol: nebulization with salbutamol at rate of 0.15ml/kg/hour every 6 hours for a duration till resolution of symptoms or 120 hours whichever is longer. Control Intervention1: Norm

Eligibility

Inclusion criteria

Inclusion criteria: respiratory distress in NBB born within 6 hours of their birth

Exclusion criteria

Exclusion criteria: Gross congenital anomaly Neonates born through meconium stained liqour Any birth trauma Any h/o birth asphyxia ( APGAR score Neonatal sepsis Radiological finding consistent with pneumonia Presence of PPHN RDS of prematurity Metabolic disorder like dysglycemia

Design outcomes

Primary

Measure	Time frame
to observe any reduction of oxygen therapy duration in interventional group as compared to placebo groupTimepoint: Outcome will be assessed after intervention at an interval of every 30 min, 1 hour and then every 2 hour subsequently till resolution of symptoms	—

Secondary

Measure	Time frame
To observe reduction in hospital stay & early initiation of feedsTimepoint: To observe reduction in hospital stay from the baseline	—

Countries

India

Contacts

Public ContactDr Safquat Jalil

INSTITUTE OF NAVAL MEDICINE

drbhatvivek@gmail.com9592296155

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026