Health Condition 1: C571- Malignant neoplasm of broad ligament Health Condition 2: C539- Malignant neoplasm of cervix uteri, unspecified Health Condition 3: C512- Malignant neoplasm of clitoris Health Condition 4: C549- Malignant neoplasm of corpus uteri, unspecified Health Condition 5: C530- Malignant neoplasm of endocervix Health Condition 6: C541- Malignant neoplasm of endometrium Health Condition 7: C531- Malignant neoplasm of exocervix Health Condition 8: C570- Malignant neoplasm of fallopi
Conditions
Interventions
Intervention1: Quadratus Lumborum block: Bilateral US-guided transmuscular QLB will be
administered at the level of L4. A 10 cm block
needle will be inserted and 25 ml of Ropivacaine (0.2%) will be
Sponsors
AIIMS, New Delhi, 110029
Eligibility
Inclusion criteria
Inclusion criteria: Participants selected will be adult patients aged 18–75 years of age with gynecological cancers and who are scheduled for cytoreductive/debulking surgery.
Exclusion criteria
Exclusion criteria: The following patients will be excluded from the study: Lack of mental ability to use a PCA pump, ASA PS grade iii and iv, obesity (BMI >30 kg/m2), any contraindication to an epidural catheter insertion (i.e. coagulopathy as defined by platelet count less than 90,000 and INR >1.5, local skin infection, etc.), patients already taking analgesics for pain, surgeries involving bowel resection, splenectomy or removal of any other organ except the uterus and adnexal masses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective will be to compare between Quadratus lumborum & epidural groups, the amount (in mg) of postoperative morphine consumed at 24 hours.Timepoint: The primary objective will be to compare between Quadratus lumborum & epidural groups, the amount (in mg) of postoperative morphine consumed at 24 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Consumption of morphine at 2, 6, 12 & 48h post operatively.Timepoint: 2 hours, 6 hours, 12 hours, 48 hours.;Numerical rating score for pain at 2, 6, 12 & 48h post operatively.Timepoint: 2 hours, 6 hours, 12 hours, 48 hours.;Incidence of complications i.e hypotension & motor blockade requiring alteration or pause in epidural administration.Timepoint: 48 hours;Time to first mobilization.Timepoint: 48 hours;Incidence of post operative nausea and/or vomiting requiring treatment.Timepoint: 48 hours;Length of hospital stay. Timepoint: Not applicable | — |
Countries
India
Contacts
Public ContactDr Anvi Gupta
AIIMS, New Delhi, 110029
Outcome results
None listed