Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intervention : Surgical site will be infiltrated with 20 ml of 0.25 mg/ml of morphine sulphate.: We aim to conduct a double blind randomized controlled trial containing two groups with
Sponsors
Sir Ganga Ram Hospital, New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Patients with -Written informed consent -Gender: Males and Females -Age: 18 - 64 years -Physical Status: ASA grade I/II
Exclusion criteria
Exclusion criteria: Patients with -Known renal dysfunction -Known hepatic dysfunction -Known endocrinal disease -History of allergy/hypersensitivity to the drugs under study -History of substance abuse -Anticipated postoperative ventilation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain evaluation during first 72 hours as assessed by Numerical rating scale (NRS). Timepoint: 30min 60min 90min 2hrs 6hrs 12hrs 24hrs 48hrs 72hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| -Requirement of first rescue analgesia in morphine sulphate & placebo (normal saline) groups from wound infiltration. -Supplemental analgesic requirement up to 72 hrs post-surgery in morphine sulphate & placebo groups after wound infiltration. -Assessment of side effects like sedation, nausea, & vomiting for 72 hrs post-surgery.Timepoint: ANALGESIC CONSUMPTION OF FENTANYL CITRATE VIA INTRAVENOUS PCA PUMP :at 1st dose then at 30 min 60 min 90 min 2 hrs 6 hrs 12 hrs 24 hrs 72 hrs DICLOFENAC SODIUM REQUIREMENT: 12-24hrs 24-48 hrs 48-72 hrs PONV (postoperative nausea & vomiting) will be assessed at 1 hr, 2 hrs, 6 hrs, 12 hrs, 24 hrs, 48 hrs & 72 hrs Richmond agitation sedation scale at 1 hr, 2 hrs, 6 hrs, 12 hrs, 24 hrs, 48 hrs & 72 hrs | — |
Countries
India
Contacts
Public ContactShivam Sharma
Sir Gangaram hospital, New Delhi
Outcome results
None listed