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Effect of Dexmedetomidine versus Paracetamol and Diclofenac on blood pressure during Laparoscopic surgeries

Comparison of Dexmedetomidine versus Paracetamol and Diclofenac on Peri-Operative Haemodynamics In Laparoscopic Cholecystectomy - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/09/057540
Enrollment
80
Registered
2023-09-13
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: Group A will be given 100mL of Normal Saline over 20 minutes followed by Injection Dexmedetomidine 1µg/kg diluted in 100mL of Normal Saline over 10 minutes preoperative

Sponsors

Jagannath Gupta Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged between 18-60 years of either sex scheduled to undergo elective laparoscopic cholecystectomy under general anaesthesia 2. American Society of Anaesthesiologists-Physical Status-1(ASA-PS-I) patients 3. Mallampatti grade 1 and 2 4. Patients weighing 45kg to 75kg

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Patients with bleeding disorder 3. Patients with known history of allergy 4. Patient with any coexisting condition like hypertension, diabetes, cardiopulmonary, hepatic, renal, metabolic diseases 5. Patients with psychiatric disease 6. Intraoperative surgical complications like laparoscopic cholecystectomy being converted to open, haemorrhage etc

Design outcomes

Primary

MeasureTime frame
Heart Rate, Mean Arterial Pressure, Sedation score & Analgesia scoreTimepoint: HR & MAP will be recorded at 0 min, 5 min, 15 min, 30 min, 45 min and 60 minutes from pneumoperitonium; Post-operative sedation and analgesia will be checked at 4, 8, 12 and 24 hours post pneumotorium in post operative period

Secondary

MeasureTime frame
need of rescue analgesiaTimepoint: Post-operative period

Countries

India

Contacts

Public ContactBarnava Pal

Jagannath Gupta Institute of Medical Sciences

senofcal@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026