Comparison between nebulisation with Dexmedetomidine and Lignocaine to attenuate laryngoscopic respone

A Comparative study between Nebulisation with Dexmedetomidine and Lignocaine to Attenuate Laryngoscopic Response in a tertiary care Centre In West Bengal - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057535

Enrollment

130

Registered

2023-09-13

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine nebulisation: Group A will be nebulised till the solution -Dexmedetomidine (1.5 µg/kg) diluted in sterile water to make 5 ml, finishes Intervention2: Dexmedetomidine neb

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients aged between 18-60 years of either sex scheduled to undergo surgery under general anaesthesia 2. American Society of Anaesthesiologists- Physical Status-1, 2 (ASA-PS-1, 2) patient 3. Modified Mallampati grade 1 and 2 4. Patients weighing between 45 kg and 75 kg

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Patients with bleeding disorder 3. Patients with known history of allergy, hypersensitivity 4. Unanticipated difficult intubation (Laryngoscopy time >15 seconds) 5. Patients with psychiatric disease 6. Pregnant lady

Design outcomes

Primary

Measure	Time frame
Heart Rate (HR) Mean Arterial Pressure (MAP)Timepoint: 1. Baseline vitals will be noted (TA) 2. Vitals will be noted just after nebulisation (TB) 3. All the vital parameters will be recorded before laryngoscopy & intubation (TC) 4. All the vital parameters will be recorded immediately after laryngoscopy & intubation(T0) 5. Vital parameters will be recorded for every 2 minutes after laryngoscopy and intubation till 10 minutes (T2, T4, T6, T8, T10)	—

Measure

Time frame

Heart Rate (HR) Mean Arterial Pressure (MAP)Timepoint: 1. Baseline vitals will be noted (TA) 2. Vitals will be noted just after nebulisation (TB) 3. All the vital parameters will be recorded before laryngoscopy & intubation (TC) 4. All the vital parameters will be recorded immediately after laryngoscopy & intubation(T0) 5. Vital parameters will be recorded for every 2 minutes after laryngoscopy and intubation till 10 minutes (T2, T4, T6, T8, T10)

—

Secondary

Measure	Time frame
noneTimepoint: n/a	—

Countries

India

Contacts

Public ContactBarnava Pal

Jagannath Gupta Institute of Medical Sciences

barnavapal@gmail.com9933552157

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026