None listed
Conditions
Interventions
Intervention1: Test food-Aloo paratha: Aloo paratha providing 25 or 50g available carbohydrates along with 125/250 ml water will be given as one of the test food once on a separate occasions.
Interven
Sponsors
Madras Diabetes Research Foundation
Eligibility
Inclusion criteria
Inclusion criteria: BMI greater than 18.5 to less than 22.9 kg/ m2 (as per WHO cut off for normal BMI) Both male and female Willingness to consume the test foods no known food allergy or intolerance; no medications known to affect glucose tolerance (excluding oral contraceptives) — stable doses of oral contraceptives, acetylsalicylic acid, thyroxin, vitamins, fibre and mineral supplements or drugs to treat hypertension or osteoporosis are acceptable.
Exclusion criteria
Exclusion criteria: a known history of diabetes mellitus or the use of anti-hyperglycemic drugs or insulin to treat diabetes and related conditions pregnant or lactating women a major medical or surgical event requiring hospitalization within the preceding 3 months; the presence of disease or drug(s) which influence digestion and absorption of nutrients; the use of steroids, protease inhibitors or antipsychotics, prebiotics, and probiotics (all of which have major effects on glucose metabolism and body fat distribution) from past 30 days. Regular use of supplements that are rich in dietary fiber or protein which influences the satiety assessment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| glycemic index, GI category of food preparations without & with dietary fibre enrichmentTimepoint: Capillary blood samples will be collected at -5,0 minutes before consumption of test and reference foods and 15,30,45,60,90,120,180,240 minutes post consumption of test and reference foods | — |
Secondary
| Measure | Time frame |
|---|---|
| The study will also elicit, the effect of the food preparations (aloo paratha & idly) without and with dietary fibre enrichment on satiety levels assessed using gut hormones-GLP-1 and PYY levelsTimepoint: Blood samples will be collected at 0 min (fasting), 60-, 120,180- & 240-minutes post consumption of intervention foods and 1 comparator glucose drink to assess selected gut hormones- GLP-1 and PYY | — |
Countries
India
Contacts
Public ContactSudha Vasudevan
MADRAS DIABETES RESEARCH FOUNDATION
Outcome results
None listed