Health Condition 1: K701- Alcoholic hepatitis
Conditions
Interventions
Intervention1: Fenugreek seed extract: Fenugreek seed extract 500 mg twice a day for 1 month
Control Intervention1: Placebo: Placebo (Maize starch IP grade) 500 mg twice a day for 1 month
Sponsors
Jawaharlal Institute of Postgraduate Medical Education Research
Eligibility
Inclusion criteria
Inclusion criteria: Alcoholic hepatitis patients of either gender aged 18–65 years with a present history of alcohol abuse as confirmed by CAGE questionnaire score =2 Patients with elevated liver enzymes levels, with AST/ALT ratio >1.5
Exclusion criteria
Exclusion criteria: Patients who are terminally ill (encephalopathy, spontaneous bacterial peritonitis, and hepatorenal syndrome) with severe alcoholic hepatitis (MDF =32), AST levels > 500 IU/L Patients with viral and drug-induced hepatitis Patients with comorbid conditions such as coronary artery disease and peripheral vascular disease Pregnant women or lactating mothers and women in reproductive age group not practicing contraceptive measures Patients who had participated in other trials in the past 3 months Patients on any other herbal medications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AST, ALT, ALP, GGT, bilirubinTimepoint: Baseline, 1 month | — |
Secondary
| Measure | Time frame |
|---|---|
| Total cholesterol, triglycerides, HDL, LDL, VLDL, hs-CRP, TNF-a, total oxidant status, total antioxidant status, adverse drug reactionsTimepoint: Baseline, 1 month | — |
Countries
India
Contacts
Public ContactSIVARANJITH L
Jawaharlal Institute of Postgraduate Medical Education & Research
Outcome results
None listed