To compare effectiveness of two drugs fentanyl citrate versus lignocaine for decreasing the pressor response during artificial tube insertion in respiratory tube under general anaesthesia.

Comparison of efficacy of intravenous fentanyl citrate versus intravenous lignocaine on hemodynamic responses to laryngoscopy and endotracheal intubation in patients under general anaesthesia . A prospective randomized double blind interventional study at SMS medical college Jaipur. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057417

Enrollment

100

Registered

2023-09-11

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: Attenuating the pressor response to laryngoscopy and endotracheal intubation under general anaesthesia: Attenuating the pressure response to laryngoscopy and endotracheal intubation by

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients belonging to ASA ( american society of anaesthesiologist ) physical status grade one and two. 2. Patients willing to give written and informed consent. 3.Patients of either sex 4.Age group 20 to 50 years

Exclusion criteria

Exclusion criteria: 1.Patients with history of known allergy to study drugs. 2.History of consumption of antihypertensive drugs ,sedatives , hypnotics ,and antidepressants preoperatively. 3.Pre-existing cardiovascular disease , significant respiratory , renal and hepatic disease . 4.History of drug and alcohol abuse.

Design outcomes

Primary

Measure	Time frame
To determine the difference in changes in heart rate from baseline to different time intervals in two groups.Timepoint: 0,1,3,5,10 minutes after intubation.	—

Secondary

Measure	Time frame
To determine the difference in changes in hemodynamic responses (SBP,DBP,MAP ) from baseline to different time intervals in two groups.Timepoint: 0,1,3,5,10 minutes after intubation.	—

Countries

India

Contacts

Public ContactDr Kana Ram Sharma

SMS Medical College Jaipur

Suncha87@yahoo.co.in9414077324

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026