Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intranasal drug instillation: Identifying the optimal dose of intranasal dexmedetomidine in reducing the stress response to intubation.
Control Intervention1: Intranasal dexmedetomidine
Sponsors
DEPARTMENT OF ANAESTHESIA
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age group: 18-60 years. 2.ASA (American Society of Anaesthesiologists) physical status I and II. 3.Elective surgeries under GA with endotracheal intubation.
Exclusion criteria
Exclusion criteria: 1.Patient with any anticipated difficult airway. 2.Patients suffering from significant cardiac, respiratory and renal disease. 3.Patient with nasal ulcers, polyps, nasal septum deviation. 4.Patient’s refusal to give consent. 5.Patient with known allergy or hypersensitivity to dexmedetomidine. 6.Patients with BMI > 35kg/m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Among three groups of intranasal dexmedetomidine probabaly 2mcg/kg may be more suitable.Timepoint: 60 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Because of its mild to moderate sedation effect peri operative patient well being will be better.Timepoint: 24hours | — |
Countries
India
Contacts
Public ContactShilpa Shivananda
S NIJALINGAPPA MEDICAL COLLEGE
Outcome results
None listed