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COMPARISON BETWEEN DIFFERENT DRUGS USED IN GIVING SPINAL ANAESTHESIA

Hyperbaric Bupivacaine, Levobupivacaine and Ropivacaine intrathecally for Hemodynamic Stability and post-operative analgesia in Infra umbilical surgeries - A Randomised control trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/09/057381
Enrollment
129
Registered
2023-09-11
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: spinal anaesthesia with hyperbaric bupivacaine: 0.5% hyperbaric bupivacaine (3ml) given intrathecally. Control Intervention1: spinal anaethesia with hyperbaric levobupivacaine and hyper

Sponsors

ROHILKHAND MEDICAL COLLEGE AND HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: POSTED FOR SURGERIES OF LOWER ABDOMEN OR LOWER LIMB OF DIFFERENT SURGICAL SPECIALITIES. CONSENT GIVEN BY PATIENT

Exclusion criteria

Exclusion criteria: NEUROLOGICAL WEAKNESS IN LOWER LIMB. ABY KNOWN ALLERGY TO LOCAL ANAESTHETICS. DERANGED COAGULATION PROFILE. RAISED ICP. LOCAL INFECTION AT SITE OF NEEDLE INSERTION.

Design outcomes

Primary

MeasureTime frame
1.Onset of sensory blockade and motor blockade. 2.Duration of sensory blockade and motor blockade. Timepoint: The patient will be evaluated for sensory and motor block, for every 3 minutes for first 30 minutes, every 5 minutes for next 30 minutes and then every 15 minutes until the sensory block has regressed to S1 dermatome.

Secondary

MeasureTime frame
5. Haemodynamic changes ( Heart Rate, Systolic Blood Pressure, Diastolic Blood Pressure, Mean Arterial Pressure ) 6. To find out any side effects/ complications like nausea, vomiting, bradycardia, hypotension. Timepoint: During the surgery the patient’s heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MBP), arterial oxygen saturation (SPO2) will be recorded every 3 mins for 30 mins and then every 5 mins for next 30 minutes, then every 15 minutes until completion of the surgery.

Countries

India

Contacts

Public ContactDR MOHD KHALIK
ANSARIKHALIK786@GMAIL.COM

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026