Health Condition 1: F410- Panic disorder [episodic paroxysmal anxiety]
Conditions
Interventions
Intervention1: Escitalopram: Starting dose of Tablet Escitalopram is 10mg per day ,once daily, orally for 4 weeks and to be continued for 12 weeks if adequate clinical response at 4 weeks.
(Adequate
Sponsors
Dr Sahil
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1)Patients meeting the diagnostic criteria of panic disorder with or without agoraphobia as per DSM-5 2)Male or female patients in the age group of 18-65 years (both inclusive). 3)Patients willing to give written informed consent. 4)Symptom onset atleast 3 months prior to enrolment in study (in case of newly diagnosed patients) or off medication for atleast 3 months prior to enrolment in study (in already diagnosed patients of panic disorder). Patients with Panic Disorder Severity Scale Score = 8 on screening.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1)Patients with Montgomery-Asberg Depression Rating Scale (MADRS) score = 20 and Generalized Anxiety Disorder Scale 7 (GAD-7) score = 10. 2)Pregnant women or nursing mothers. 3)Women planning to conceive. (in patient consent form it has been included that patient will not conceive for next 8 weeks) 4)Patient’s symptoms are associated with or attributable to an identifiable cause such as Hyperthyroidism, Asthma, Cardiovascular diseases (like angina, congestive heart failure etc ) or Substance use disorder. 5)Patients with known history of dyslipidemia. 6)Patients with diabetes mellitus, uncontrolled hypertension, heart block, bradycardia (pulse 7)History of acute myocardial infarction or stroke. 8)Patients having history suggestive of psychosis or dementia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Severity of Panic attacks. 2. Frequency of panic attacks. 3. Percentage of patients free from full symptom panic attacks.Timepoint: 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Percentage of Responders. 2. Need for rescue medication.Timepoint: 12 weeks | — |
Countries
India
Contacts
Public ContactDr Manish Thakre
Government Medical College and Hospital, Nagpur
Outcome results
None listed