Health Condition 1: O- Medical and Surgical Health Condition 2: H748- Other specified disorders of middle ear and mastoid
Conditions
Interventions
Intervention1: Dexmedetomedine- Drug
Alpha agonist: In intervention group we will assess the effect of intraoperative infusion of 0.6mcg/kg dexmedetomedine infusion during extubation in the last 15 mi
Sponsors
Jawaharlal Nehru Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Patients of physical status I and II according to American Society of Anesthesiologists (ASA) who are without comorbidities ,scheduled for elective middle ear surgery under general anaesthesia.
Exclusion criteria
Exclusion criteria: Patients with severe obesity (body mass index greater than 35), renal insufficiency (serum creatinine more than 1.6 mg/dl), liver dysfunction (serum glutamic oxaloacetic transaminase/ serum glutamic pyruvic transaminase values more than 50% of normal), patients with difficult airways, cardiorespiratory abnormalities (Diabetes, Hypertension, New York Heart Association heart failure grades 3 and 4, obstructive and restrictive lung diseases), , pregnant, currently breast feeding women, history of sleep apnea planned / emergency surgeries in neck and oral cavity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infusion of Dexmedetomidine prior to endotracheal extubation will act on suppression of haemodynamic stress responseTimepoint: 30 minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not applicableTimepoint: Not applicable | — |
Countries
India
Contacts
Public ContactJayashree Sen
Datta Meghe Institute of Higher Education and Research
Outcome results
None listed