A clinical study to assess postoperative analgesic effects of Quadratus lumborum block with dexmedetomidine after open inguinal herniotomy and hydrocele surgery in children

Efficacy of ultrasund guided quadratus lumborum block with dexmedetomidine for postoperative analgesia after open inguinal herniotomy and hydrocele surgeries in children - a randomised control trial - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057338

Enrollment

Registered

2023-09-06

Start date

Unknown

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N433- Hydrocele, unspecified Health Condition 2: N432- Other hydrocele Health Condition 3: K409- Unilateral inguinal hernia, without obstruction or gangrene

Interventions

Intervention1: Quadratus lumborum block with bupivacaine and dexmedetomidine: 0.5ml/kg of 0.25% Bupivacaine with 1 microgram/kg of dexmedetomidine with appropriate amount of saline given after inducti

Eligibility

Inclusion criteria

Inclusion criteria: All children ASA 1/2 under the age of 18 years posted for unilateral inguinal hernia and hydrocele surgery will be included in the study.

Exclusion criteria

Exclusion criteria: 1. ASA 3/4 2. History of liver and renal disorders 3. Coagulopathies and bleeding disorder 4. Infection at injection site 5. Allergy to local anaesthetic/ paracetamol 6. Patient and Guardian refusal

Design outcomes

Primary

Measure	Time frame
Time to first analgesicTimepoint: 1. Time from the block is given till the patient has a pain score of more than 3 will be observed. 2. Pain scores will be assessed from immediate post extubation till upto 36 hours. 3. Time to first paracetamol dose required will be calculated from the time block is given. 4. In case within 6 hours of paracetamol the patient has a pain score of more than 3, he/ she will be given Ibuprofen 7 mg/kg body weight.	—

Measure

Time frame

Time to first analgesicTimepoint: 1. Time from the block is given till the patient has a pain score of more than 3 will be observed. 2. Pain scores will be assessed from immediate post extubation till upto 36 hours. 3. Time to first paracetamol dose required will be calculated from the time block is given. 4. In case within 6 hours of paracetamol the patient has a pain score of more than 3, he/ she will be given Ibuprofen 7 mg/kg body weight.

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Secondary

Measure	Time frame
Intraoperative & postoperative complicationsTimepoint: Incidence of bradycardia, hypotension, respiratory depression, vomiting & pruritis;Post operative pain scoresTimepoint: Every 5 minutes post extubation, at 30 minutes, 1 hour, 1 1/2 hours, 2 hours, 6 hours, 12 hours,18 hours, 24 hours, 36 hours post extubation;Requirement of rescue analgesicTimepoint: Requirement of rescue analgesic in addition to paracetamol;Total paracetamol dosesTimepoint: Total number of paracetamol doses given in the first 36 hours post block	—

Measure

Time frame

Intraoperative & postoperative complicationsTimepoint: Incidence of bradycardia, hypotension, respiratory depression, vomiting & pruritis;Post operative pain scoresTimepoint: Every 5 minutes post extubation, at 30 minutes, 1 hour, 1 1/2 hours, 2 hours, 6 hours, 12 hours,18 hours, 24 hours, 36 hours post extubation;Requirement of rescue analgesicTimepoint: Requirement of rescue analgesic in addition to paracetamol;Total paracetamol dosesTimepoint: Total number of paracetamol doses given in the first 36 hours post block

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Countries

India

Contacts

Public ContactDr. Aruna Parameswari

Sri Ramachandra Medical College and Research Institute

hod.anaesthesiology@sriramachandra.edu.in09840529863

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026