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Comparative study of uterotonic agents in the prevention of post partum haemorrhage following vaginal delivery

Comparative study of Carbetocin vs Oxytocin in the prevention of post partum haemorrhage following vaginal delivery - NIL

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/09/057333
Enrollment
116
Registered
2023-09-06
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O720- Third-stage hemorrhage

Interventions

Intervention1: Intravenous Administration of injection Carbetocin: Injection Carbetocin 100 micrograms single dose intravenous route will be administered without any other confounding factor to subjec

Sponsors

Ramaiah medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: (1) at or beyond 28 gestational weeks; (2) 18–45 years old; (2) at least one risk factor for developing atony.

Exclusion criteria

Exclusion criteria: Participants with cardiovascular disorders, hepatic or renal disease, epilepsy, known allergies to oxytocin or carbetocin.

Design outcomes

Primary

MeasureTime frame
The aim of the study is to compare the effects of carbetocin with those of oxytocin in several dosing regimens for the prevention of uterine atony in patients undergoing full term vaginal delivery. The outcome is assessed in terms of blood loss, need for additional uterotonic agents, fall in blood pressure, side effects of the drug Carbetocin if any Timepoint: Outcome is assessed immediately after delivery and 12 hours, 24 hours after delivery.

Secondary

MeasureTime frame
This study is aimed at comparing the effects of carbetocin vs oxytocin in prevention of postpartum hemorrhage following vaginal delivery in terms of: Secondary outcomes - Fall in hb Requirement of additional uterotonic agents Adverse effects Need for blood transfusionTimepoint: Outcome is assessed immediately after delivery, 12 hours & 24 hours

Countries

India

Contacts

Public ContactRevathi Mallikarjuna

Ramaiah Medical College and teaching hospital

mamatha750@yahoo.com9535208686

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026