Health Condition 1: - Health Condition 2: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Control Intervention1: NIL: NIL
Sponsors
DHR/ ICMR Grant in aid scheme 2022
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria for test group 1. Age >18-50 years 2. Patients scheduled to undergo laparoscopic/open cholecystectomy 3. Patients with normal serum vit D level in pre-operative period Inclusion Criteria for control group 1. Age 18-50 years 2. Patients scheduled to undergo surgery other than cholecystectomy eg hernia repair, SFJ ligation and stripping for varicose vein, etc 3. Patients with normal serum vit D level in pre-operative period
Exclusion criteria
Exclusion criteria: Exclusion criteria test group 1. Patients with significant liver or renal disease 2. Patients with gastrointestinal malabsorptive disorders eg. Celiac disease 3. Patients already on vit D supplement 3 months prior to surgery 4. Patients with previous history of surgery interfering with vit D metabolism eg. Parathyroid surgery, renal transplant, bariatric surgery, terminal ileal resection. 5. Patients with endocrine disorders eg. parathyroid deficiency. 6. Patients with acute cholecystitis 7. Patient refusal to give consent to participate in the study Exclusion criteria control group 1. Patients with significant liver or renal disease 2. Patients with gastrointestinal malabsorptive disorders eg. Celiac disease 3. Patients already on vit D supplement 3 months prior to surgery 4. Patients with previous history of surgery interfering with vit D metabolism eg. Parathyroid surgery, renal transplant, bariatric surgery, terminal ileal resection. 5. Patients with endocrine disorders eg. parathyroid deficiency. 6. Patients undergoing emergency surgery 7. Patient refusal to give consent to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To measure the impact of cholecystectomy over vit D3 level including time to reach the insufficient/deficient level & also to evaluate proportion of patients in each group having insufficient/deficient level at each point of time.Timepoint: baseline, 1month, 3 month , 6 month | — |
Secondary
| Measure | Time frame |
|---|---|
| Trend in vit d level in both the groupTimepoint: preop within 3 weeks, & 1,3,6 months in follow up | — |
Countries
India
Contacts
Public ContactDr Agrawal Kavita Khemchand
Dr. B. R. Ambedkar State Intitute of Medical Sciences, mohali
Outcome results
None listed