Health Condition 1: F20- Schizophrenia
Conditions
Interventions
Intervention1: Cariprazine: Antipsychotic drug
Dose: 1.5-6 mg
Frequency: daily
Route: oral
Duration: 10 weeks
Control Intervention1: Risperidone: Antipsychotic drug
Dose: 2-16 mg
Frequency: daily
Rout
Sponsors
Government Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Persons diagnosed with Schizophrenia as per ICD-11. 2. Persons of all genders, aged between 18-65 years. 3. Drug naïve patients only. 4. Duration of illness not more than 2 years. 5. Patients or Nominated representatives (in case of patients who lack capacity for making decisions for treatment as per Mental Healthcare Act-2017) willing to give consent for the study. 6. Patients being accompanied by reliable informants.
Exclusion criteria
Exclusion criteria: 1. Patients with neurological disorders - head injury, tumours, dementia, organic brain syndromes (e.g. delirium, amnesia), epilepsy. 2. Patients with co-morbid substance dependence (except Nicotine and Caffeine). 3. Patients who are lactating or pregnant. 4. Patients with Intellectual disability. 5. Actively suicidal patients. 6. Patients with any acute, unstable medical/surgical illnesses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the severity of psychiatric symptomatology as measured by PANSS, BPRS.Timepoint: 0, 2, 4, 7, 10 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Effect of treatment on quality of life, current functioning & neuropsychological assessments as measured on CDSS, WHOQOL BREF, GASS, SOFS, CGI, ASEX, MOCA, blood & other related investigations.Timepoint: 0, 2, 4, 7, 10 weeks | — |
Countries
India
Contacts
Public ContactDr Ajeet Sidana
Government Medical College and Hospital, Sector 32, Chandigarh
Outcome results
None listed