Comparison of effects of dexmedetomidine added to levobupivacaine and recemic bupivacaine for cesarean section under spinal anaesthesia.

To determine the time of onset, time to attainment of maximum level and duration of sensory and motor blockade with Levobupivacaine heavy with Dexmedetomidine versus Racemic Bupivacaine Heavy with Dexmedetomidine in Spinal Anaesthesia for Cesaean Section - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057280

Enrollment

130

Registered

2023-09-06

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O99- Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium

Interventions

Intervention1: Levobupivacaine heavy with Dexmedetomidine: under full aseptic precaution, 0.5% levo bupivacaine heavy 2 ml with inj dexmedetomidine 5 micro gm will be given for spinal anaesthesia in L

Eligibility

Inclusion criteria

Inclusion criteria: The patient giving informed and written consent for study. Primigravida posted for elective caesarean section with more than 37 weeks gestation. Having singleton pregnancy.

Exclusion criteria

Exclusion criteria: The patient not giving consent for the study. Pregnancy with height less than 145cm and more than 165cm. patients having any contraindications for spinal anaesthesia. Pregnant women with fetal anomaly, placenta previa, abruptio placenta, placenta percreta or increta.

Design outcomes

Primary

Measure	Time frame
To determine the time of onset, time to attainment of maximum level & duration of sensory and motor blockade.Timepoint: time of onset: zero minutes Time to attainment of maximum level: time taken to reach anaesthesia at T6 dermatomal level. Duration of sensory and motor blockade: from the time of induction (zero minutes) to regression of anaesthesia at T12 and movement of lower limb respectively.	—

Secondary

Measure	Time frame
To record the haemodynamic parameters every minute in first 15 minute after giving spinal anaesthesia, there after every 5 minutes. To record APGAR score of the new born in recommended time afrer delivery. To determine the time of requirement of first rescue analgesic To find out incidence of side effets during the operative procedure & upto the requirement of rescue analgesic in both the groupTimepoint: Every minute in first 15 minute after giving spinal anaesthesia, there after every 5 minutes.	—

Measure

Time frame

To record the haemodynamic parameters every minute in first 15 minute after giving spinal anaesthesia, there after every 5 minutes. To record APGAR score of the new born in recommended time afrer delivery. To determine the time of requirement of first rescue analgesic To find out incidence of side effets during the operative procedure & upto the requirement of rescue analgesic in both the groupTimepoint: Every minute in first 15 minute after giving spinal anaesthesia, there after every 5 minutes.

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Countries

India

Contacts

Public ContactDr Mukesh Kumar

RAJENDRA INSTITUTE OF MEDICAL SCIENCES, RANCHI

shrivastava2911@gmail.com9958912712

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026