Regeneration of bone is being assessed using a novel technique by combining bio-materials to hasten the process of bone healing in the region of the lower wisdom tooth after its removal.

The combined efficacy of Colloidal silver, Biphasic calcium phosphate in mandibular third molar impactions using trephine technique. – A randomized control trial. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057278

Enrollment

Registered

2023-09-06

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Surgical removal of 3rd molar using trephination technique.: route : sub - periosteum frequency: 1 duration (follow up ) : 1st week 5th week 13th week & 20th week. Intervention2: B

Eligibility

Inclusion criteria

Inclusion criteria: Patients with position B and C impacted teeth. (Pell And Gregory Classification) Skeletally matured patients. Radiographically bilaterally symmetrical impactions. ASA I and ASA II Therapeutic impactions (required for orthodontic extractions and prosthetic rehabilitation)

Exclusion criteria

Exclusion criteria: Medically compromised patients systemically contraindicated for surgery. Reported allergy or hypersensitivity to any of the products used in the study which include allergy or hypersensitivity to Silver. ASA III and ASA IV Bony pathologies. Non -compliance patients Chronic smokers.

Design outcomes

Primary

Measure	Time frame
To understand colloidal silver along with Biphasic Calcium Phosphate as a growth adjunct in deep seated impacted mandibular third molars Postoperative hard tissue healing at regular intervals using OPG Timepoint: Bone regeneration assessed at 1st 5th 13th & 20th week post operatively	—

Secondary

Measure	Time frame
Assessment of hemostasis. Timepoint: Immediate post operative bleeding assessment. ;To assess soft tissue healing using Early Wound Healing ScoreTimepoint: 1st & 5th week	—

Countries

India

Contacts

Public ContactN Komagan Prabhu

SRM Dental college, Ramapuram

komagan.prabhu@gmail.com9962004554

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026