Health Condition 1: F312- Bipolar disorder, current episodemanic severe with psychotic features Health Condition 2: F22- Delusional disorders Health Condition 3: F333- Major depressive disorder, recurrent, severe with psychotic symptoms Health Condition 4: F323- Major depressive disorder, singleepisode, severe with psychotic features Health Condition 5: F302- Manic episode, severe with psychotic symptoms Health Condition 6: F20- Schizophrenia
Conditions
Interventions
Intervention1: nil: nil
Control Intervention1: nil: nil
Sponsors
Institutional Ethical Commitee, Maulana Azad Medical College and Associated Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1 Age should be between 18-60years at the time of admission in psychiatry ward 2.Consecutive admitted patients meeting the criteria for either diagnosis of schizophrenia (F20), persistent delusional disorder (F22.0), psychotic mania (F30.2 & F31.2) and psychotic depression (F32.3 & F33.3) as specified by the ICD-10 Classification of Mental and Behavioural Disorder, Diagnostic criteria for research (ICD-10 DCR)18 with predominance of monothematic (delusional beliefs that are all related to a single theme) non bizarre delusion with or without hallucination 3.Patients should be drug free for last weeks during acute phase presentation 4.Patients should be cooperative for the assessment and accompanied by at least one informant.
Exclusion criteria
Exclusion criteria: 1) Duration of current psychotic mania and psychotic depression is more than 6 months. 2) Patients having any hearing or vision problems. 3) Co-morbid dependence on any psychoactive substance (except tobacco) and other major psychiatric illness (e.g., schizoaffective disorder, dysthymia, catatonic features) 3) Head injury, epilepsy or any structural brain lesion or organic brain syndrome (based on clinical examination and investigation reports), dementia any endocrinological illness or taking the treatment for the same. 4) Those patients who are not coming for follow-up after 1 month +one week or were not compliant with medication (i.e. below the level of assured/confirmed) 5) When current relapse is a breakthrough (reappearance of symptoms despite the continuation of an adequate dose of drugs)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) Level of delusional belief(assessed by Brown Assessment Of Belief Scale) at the initiation of treatment & follow up visits 2) Level of insight (assessed by Schedule for Assessment of Insight Expanded version) at the initiation of treatment & follow up visitsTimepoint: baseline 1 month 3 month 6 month | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Severity of psychosis in schizophrenia & delusional disorder (assessed by Brief Psychiatric Rating Scale), depression with psychotic symptoms (assessed by Hamilton Depression Rating Scale 17) and mania with psychotic symptoms patients (assessed by Young Mania Rating Scale) at the initiation of treatment and follow up visits 2) Level of functioning (as assessed by Global Assessment of Functioning Scale) in these patients at the initiation of treatment and follow up visits.Timepoint: Baseline 1 month 3 month 6 month | — |
Countries
India
Contacts
Public ContactPartha Sarathi Biswas
GB Pant Institute of PG medical education and research
Outcome results
None listed