Management of early avascular necrosis of femoral head by core decompression with bisphosphonate therapy versus core decompression

Randomized control trial on management of early avascular necrosis of femoral head by core decompression with bisphosphonate therapy versus core decompression

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/09/057253

Enrollment

Registered

2023-09-05

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Core decompression: Core decompression - reduces the elevated intraosseous pressure in the femoral head leading to increased blood flow thereby promoting new bone formation and healing.

Eligibility

Inclusion criteria

Inclusion criteria: 1. Skeletally mature patients 2. Cases of Avascular Necrosis of femoral head in stage 1 and stage 2 of any etiology 3. Cases willing to undergo surgery for inclusion in one / both hips .

Exclusion criteria

Exclusion criteria: 1. Previously operated hips 2. Cases having arthritic changes in involved hip 3. Cases unwilling for surgery

Design outcomes

Primary

Measure	Time frame
At the end of study , their might be probable improvement in Patients managed with Core decompression with bisphosphonate therapy for the treatment of early AVN of the femoral head when compared to management with core decompression onlyTimepoint: 3 weeks , 6 weeks , 3 months , 6 months , 9 months , 12 months	—

Secondary

Measure	Time frame
NilTimepoint: Nil	—

Countries

India

Contacts

Public ContactDr Ashutosh Lohiya

Datta Meghe Institute of Higher Education and Research ,Sawangi Meghe, Wardha

nsdhaniwala@gmail.com9422188450

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026