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Understanding sleep problems in patients with gum disease and over weight: A study on two potential markers.

The role of salivary Visfatin and IL-6 as potential predictive markers of Obstructive Sleep Apnea in Patients with coexisting stage III/IV Periodontitis and Obesity: an observational study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/09/057235
Enrollment
76
Registered
2023-09-04
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: E663- Overweight

Interventions

Intervention1: Nil: nil Control Intervention1: Nil: Nil

Sponsors

Maajida Aafreen M
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pristine periodontal health: 1 No bleeding on probing 2 Normal gingival sulcus depth 3 Normal bone heights 4 Controlled modifying factors Clinical periodontal health (intact periodontium): 1 No or minimal bleeding on probing 2 Normal gingival sulcus depth 3 Normal bone heights 4 Controlled modifying factors 5 Controlled predisposing factors Stage III periodontitis: 1 Interdental clinical attachment loss at site of greatest loss greater than or equal to 5mm 2 Radiographic bone loss extending to middle or apical third of root 3 Tooth loss due to periodontitis less than or equal to 4 teeth 4 Probing depth greater than or equal to 6mm. 5 Extent: Greater than 30 percentage of teeth involved (Generalized) Stage IV periodontitis: 1 Interdental clinical attachment loss at site of greatest loss greater than or equal to 5mm 2 Radiographic bone loss extending to middle or apical third of root 3 Tooth loss due to periodontitis greater than or equal to 5 teeth 4 Extent: Greater than 30 percentage of teeth involved (Generalized) Inclusion criteria for obesity: According to Centers for Disease Control and Prevention(CDC): BMI evaluation will be done by measuring the weight (in kgs) and height (in cms) to determine the body size. With the metric system, the formula for BMI is weight in kilograms divided by height in meters squared. 30.0 to less than 35.0-Class 1 obesity 35.0 to less than 40.0-Class 2 obesity 40.0 or over-Class 3 obesity ( also known as morbid, extreme, or severely obese)

Exclusion criteria

Exclusion criteria: 1 Patients with other systemic inflammatory conditions like diabetes, hypertension, chronic kidney disease, chronic respiratory infections, cancers, asthma, HIV and hepatitis will be excluded from the study 2 History of periodontal treatment within the previous 6 months 3 Smoking and alcohol consumption 4 Pregnant and lactating women 5 History of antibiotic therapy in the past 3 months

Design outcomes

Primary

MeasureTime frame
To correlate the salivary levels of visfatin and IL6 and clinical parameters of periodontitis and obesity with the risk of developing obstructive sleep apnea Timepoint: Baseline

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDr. Priyanka Cholan

SRM Dental College

priyankacholan@gmail.com9840771507

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026