Health Condition 1: K132- Leukoplakia and other disturbancesof oral epithelium, including tongue
Conditions
Interventions
Intervention1: platelet rich fibrin as a graft material: After surgical excision of oral mucosal lesions, Platelet-rich fibrin will be placed as a graft material. The study outcomes will be recorded o
Sponsors
Lady Hardinge Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with oral mucosal lesions of size less than 5 cm in its greatest dimension. 2. Age group- 18-60 years
Exclusion criteria
Exclusion criteria: 1. With systemic diseases like diabetes mellitus, hypertension, thyroid disorders, immunocompromised state, etc. 2. H/O chemotherapy or radiotherapy 3. On long-term antibiotic, steroid or antiplatelets 4. Active local and/or systemic infection 5. Pregnant and lactating women and those taking oral contraceptives. 6. Hemoglobin level less than 10 gm/dL 7. Platelet count less than 100 ×103/µL 8. H/O allergy to local anesthetic agents like Xylocaine. 9. Chronic Alcoholic- >4 drinks/day or 14-15 drinks in a week. 10. Smoker- 100 cigarettes in his/her lifetime or currently smokes cigarettes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Comparison of IPR healing scores between group 1, group 2 & group 3Timepoint: post-operative 4th day, 14th day, 6 weeks between the three groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Comparison of scores of VAS for severity of pain assessment 2.To record & compare the presence the granulation tissue formed 3.To record and compare the epithelization of wound 4.To record and compare the wound contracture 5.To record and compare any complicationsTimepoint: post-operative 4th day, 14th day, 6 weeks between the three groups | — |
Countries
India
Contacts
Public ContactPooja Jain
Lady Hardinge Medical College
Outcome results
None listed