Health Condition 1: R00-R99- Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Conditions
Interventions
Intervention1: De-resuscitation based on VExUS grading: patients randomized to VExUS group will receive de-resuscitation based on VExUS grading algorithm. if IVC 2cm patient will be recruited, hepatic
Sponsors
AIIMS, Bhubaneswar
Eligibility
Inclusion criteria
Inclusion criteria: adults >18 years admitted in SICU/CICU/HDU. patients requiring aggressive fluid resuscitation in 24 hours . expected ICU stay > 48 hours Inferior vena cava diameter > 2 cm at any point of ICU stay after 24 to 48 hours post admission.
Exclusion criteria
Exclusion criteria: refusal to give consent known cases of cirrhosis with portal hypertension and IVC thrombus. pregnant inadequate acoustic window prediction of ICU stay less than 48 hours in ICU/HDU
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| cumulative fluid balance on days 3 & 5 of recruitment organ failure indices -p/f ratio, serum creatinine, Delta SOFA score duration of mechanical ventilation in hours length of ventilation in hours incidence of new onset hypernatremia and metabolic alkalosis mortality at ICU/wardTimepoint: day 3 & day 5 post recruitment | — |
Primary
| Measure | Time frame |
|---|---|
| To compare the cumulative fluid balance on day 4 of recruitment between the intervention group & control group ( measured in ml, expressed as mean with SD)Timepoint: day 4 of recruitment | — |
Countries
India
Contacts
Public ContactDr Sumana S
All India Institute of Medical Sciences Bhubanewsar
Outcome results
None listed