Health Condition 1: C50- Malignant neoplasm of breast
Conditions
Interventions
Intervention1: Glutamine powder 10 grams orally with water once daily(OD) for 4 days starting 24 hours after each chemotherapy cycle: Glutamine powder 10 g orally with water once daily for 4 days star
Sponsors
Jawaharlal Nehru Medical College Aligarh Muslim University Aligarh
Eligibility
Inclusion criteria
Inclusion criteria: Breast cancer diagnosed patients who are advised chemotherapy Patients willing to participate after informed consent Age 18 years and above Normal performance status (ECOG 2) Adequate renal and liver function No co- morbidities
Exclusion criteria
Exclusion criteria: Hypothyroidism or hyperthyroidism Diabetes mellitus Previously diagnosed neuropathy Pre existing autoimmune disease Anti tubercular OR Anti viral therapy Congestive heart failure, liver failure or renal failure Chronic anemia Chronic alcoholism, chronic smoking or drug abuse Previously chemotherapy received
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuroprotective effect of glutamine on chemotherapy induced peripheral neuropathyTimepoint: Baseline, then serially after chemotherapy cycle and at chemotherapy completion | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in quality of of life after preventive therapyTimepoint: Baseline, after chemotherapy cycle & full completion of chemotherapy | — |
Countries
India
Contacts
Public ContactDr Naureen Rizvi
Department of Physiology, Jawaharlal Nehru medical college, AMU Aligarh
Outcome results
None listed