Skip to content

Inhalation anesthesia with sevoflurane vs intravenous anesthesia with propofol and dexmedetomidine on postoperative nausea vomiting and recovery parameters after anesthesia

Comparison of inhalational anesthesia (Sevoflurane) and total intravenous anesthesia with propofol, dexmedetomidine on postoperative nausea and vomiting and postoperative recovery parameters in laparoscopic surgery - A prospective randomized controlled trial. - Nil

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/057104
Enrollment
80
Registered
2023-08-30
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N838- Other noninflammatory disorders ofovary, fallopian tube and broad ligament

Interventions

Intervention1: Sevoflurane: During intraoperative maintenance of anesthesia (1% to 3%) Control Intervention1: Dexmedetomidine and Propofol: Bolus dose of Dexmedetomidine 1 mcg/kg over 15 min before in

Sponsors

Apollo Hospitals Bilaspur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I and II Scheduled for laparoscopic surgery under general anesthesia

Exclusion criteria

Exclusion criteria: 1. Known allergy to study drug. 2. Use of antiemetic drug within 24 hour of surgery. 3. Morbid obesity (BMI >40) 4. Chronic use of opioids. 5. Patient with hepatic , renal and cardiovascular dysfunction. 6. Psychiatric patients. 7. Patient with history of motion sickness.

Design outcomes

Primary

MeasureTime frame
Postoperative nausea & vomitingTimepoint: 24 hour postoperative period

Secondary

MeasureTime frame
1. Extubation time (minute) 2. Respond to verbal command (minute) 3. Orientation time (minute) Timepoint: Postoperative period

Countries

India

Contacts

Public ContactDr Vinit Kumar Srivastava

Apollo Hospitals Bilaspur

drvinit75@gmail.com9755557539

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026