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Comparison of neurocognitive outcomes in patients with aneurysmal subarachnoid haemorrhage following clipping Vs coiling of anterior circulation

Comparison of neurocognitive outcomes in patients with good grade aneurysmal subarachnoid haemorrhage following clipping Vs coiling of anterior circulation aneurysm; a prospective observational pilot study - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/08/057088
Enrollment
50
Registered
2023-08-30
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G938- Other specified disorders of brain

Interventions

Control Intervention1: compare neurocognition in clipping vs coiling in aneurysmal SAH: it is a observational study and neurocognition tests are used to compare clipping vs coiling patients in aneurys

Sponsors

K Pradeep
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: WFNS grades 1 and 2. Both genders. Age 18-65 years, undergoing both clipping and coiling of cerebral aneurysm in the neurosurgery operation theatre and neuro-interventional suite.

Exclusion criteria

Exclusion criteria: WFNS grade 3-5 Age 65 years. Severe or uncompensated cardiovascular, renal, hepatic or endocrine disease. Pregnancy, postpartum, lactating females. Refusal to consent by the patient or next of kin. Tracheostomized Patients.

Design outcomes

Primary

MeasureTime frame
ACE III score at admission, & discharge. 1 month follow up: Number of errors are noted in Trail making, Letter digit substitution test, Stroop test, ACE III, and Wechsler memory scale (visual reproduction). Timepoint: ACE III score at admission, & discharge. 1 month follow up: Number of errors are noted in Trail making, Letter digit substitution test, Stroop test, ACE III, and Wechsler memory scale (visual reproduction).

Secondary

MeasureTime frame
Baseline & postoperative vitals: heart rate, systolic blood pressure, diastolic blood pressure, mean blood pressure, saturation. Date of Ictus. SAH grade. ICU Duration. Duration of hospital stay. Type of anaesthesia: Inhalational / TIVA Maintenance, an additional opioid used, intraoperative complications, temporary clipping duration, other analgesics, antiepileptic: Duration of procedure Postoperative complications (like vasospasm, delayed cerebral ischemia, hydrocephalus, & related treatment). GOS score at discharge Timepoint: AT ADMISSION DISCHARGE

Countries

India

Contacts

Public ContactS Manikandan

Sree Chitra Tirunal Institute for Medical Sciences and Technology

kanmanis@sctimst.ac.in9446334711

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026