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Postoperative pain in patients after cardiac surgery can be reduced by using pregabalin or magnesium sulphate or their combination

The Analgesic Potential Of Preoperative Oral Pregabalin Intravenous Magnesium Sulphate And Their Combination In Acute Post Thoracotomy Pain In Cardiac Surgery: A Double-Blinded Randomized Study - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/057084
Enrollment
75
Registered
2023-08-30
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: General Anaesthesia: Comparative drugs Pregabalin or Magnesium Sulphate or both will be given before intubation and their effects on Postoperative pain will be assessed in postoperative

Sponsors

DR SN Medical CollegeJodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: : The patients of age 19-70yrs of either gender of ASA category II or III undergoing cardiac surgeries under general anesthesia who are hemodynamically stable and declared fit in preanesthetic checkup.

Exclusion criteria

Exclusion criteria: 1.Patient refused to participate in study. 2.Known sensitivity or contraindication to drugs used in the study 3.History of psychological disorders (e.g. patients on antidepressants or anti psychotic medications) 4.Patients on regular opioid medications for chronic pain (i.e. pain more than 3 months) 5.Patients with documented impairment of hepatic and/or kidney functions.

Design outcomes

Primary

MeasureTime frame
Total doses of rescue analgesia in 24 hours: We will note the total doses of rescue analgesia given to the patient in 24 hrs post-operative period. Consumption of inj. fentanyl in the post-operative period will be seen for complete 24 hrs in the entire three groups. This will be seen as reference for the analgesic efficacy of the combination of Pregabalin & magnesium sulphate usage. Timepoint: 24hr

Secondary

MeasureTime frame
Total doses of rescue analgesia in 24 hours: We will note the total doses of rescue analgesia given to the patient in 24 hrs post-operative period. Consumption of inj. fentanyl in the post-operative period will be seen for complete 24 hrs in the entire three groups. This will be seen as reference for the analgesic efficacy of the combination of Pregabalin & magnesium sulphate usage. Timepoint: 1 HOUR

Countries

India

Contacts

Public ContactDr Rakesh Karnawat

DR SN Medical College,Jodhpur,Rajasthan

dr.rakeshkarnawat@yahoo.com9828033321

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026