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Computer task based treatment in depression

To Study the effect of cognitive training task on attention, prefrontal cortical activity, heart rate variability and serum cortisol in adult patients (18-55 years) with depression: Single blinded, randomized control trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/057082
Enrollment
180
Registered
2023-08-30
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F320- Major depressive disorder, singleepisode, mild Health Condition 2: F321- Major depressive disorder, singleepisode, moderate Health Condition 3: F330- Major depressive disorder, recurrent, mild Health Condition 4: F331- Major depressive disorder, recurrent, moderate

Interventions

Intervention1: Cognitive training on computer/screen: Four cognitive domains viz. attention, decision making, impulse control and working memory will be used in the cognitive training. Each cognitive

Sponsors

AIIMS Nagpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 18-55 years both genders, Diagnosis according to ICD 10 (F32.00-10 & 33.00-10) by psychiatrist (only for patient group), normal or corrected to normal vision (6/6 according to Snellen chart), normal color vision assessed by ishihara chart.

Exclusion criteria

Exclusion criteria: Any history secondary causes of cognitive impairment (like history of stroke, brain injury, exposure to toxins or neuroleptics, history of neurological disease, dementia, Alzheimer’s disease or any neurological illness with significant cognitive impairment), Montreal Cognitive Assessment (MoCA)score <26. Patients on any drugs other than antidepressants that can affect cardiac autonomic functions like antihistaminics, cough or cold medications, diuretics, sympathomimetics, parasympathomimetics will be excluded from the study. Severe depression with or without psychotic symptoms.

Design outcomes

Primary

MeasureTime frame
Improvement in prefrontal cortical activity after cognitive trainingTimepoint: Baseline, 4 weeks, 8 weeks and 12 weeks

Secondary

MeasureTime frame
NilTimepoint: nil

Countries

India

Contacts

Public ContactDr Ashlesh Patil

AIIMS Nagpur

dr.ashlesh.p@gmail.com9650344666

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026