Effect of platelet rich plasma (PRP) in knee pain with osteoarthritis knee

Effect of intra-articular platelet rich plasma(PRP)injection in patients with knee osteoarthritis with osteochondral lesions of knee: A prospective interventional study. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/057065

Enrollment

Registered

2023-08-30

Start date

Unknown

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Injection platelet rich plasma (PRP): injection of platelet rich plasma in knee osteoarthritis with osteochondral lesions Intervention2: Platelet rich plasma (PRP) injetion: Injection p

Eligibility

Inclusion criteria

Inclusion criteria: 1 Age 30 to 60 years 2 Knee osteoarthritis stage 1 to 3 according to ACR guidelines 3 Documented osteochondral lesion on MRI 4 Hemoglobin >10 gm% 5 Platelet count >1.5 lakh/cumm

Exclusion criteria

Exclusion criteria: 1 Anaemia 2 Any bleeding dyscrasias or coagulopathies 3 Uncontrolled diabetes mellitus 4 Having a medical condition that could worsen or spread with injections, such as an active infection, a metastatic disease, or skin diseases 5 Pregnancy 6 Undergoing anticoagulation therapy 7 History of any steroid or any other injection in the knee taken upto 6 months before. 8 History of any surgical intervention done in the knee upto 6 months before. 9 History of any prior trauma to the knee before the symptom onset 10 Any autoimmune or rheumatic disease involving the knee 11 Any neurological deficit in the lower limb 12 Severe mechanical deformity (Varus or Valgus > 15 degrees)

Design outcomes

Primary

Measure	Time frame
VAS AND KOOS SCORESTimepoint: baseline , 1 week, 1 month, 3 month and 6 months	—

Secondary

Measure	Time frame
Change in MRI in the osteochondral lesionTimepoint: baseline & 6 months	—

Countries

India

Contacts

Public ContactDr Mahesh Choudhary

All India Institute of Physical Medicine and Rehabilitation Keshavrao Khadye Marg Hajiali Mumbai

drmahichoudhary@gmail.com9920083839

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026