Health Condition 1: N219- Calculus of lower urinary tract, unspecified
Conditions
Interventions
Intervention1: SILODOSIN: SILODOSIN 8 mg tablet once daily per-orally after dinner before bed-time (HS) for 1 year
Control Intervention1: MIRABEGRON: MIRABEGRON 50 mg tablet once daily per-orally aft
Sponsors
Dr Rajendera Prasad Government Medical College, Kangra at Tanda, Himachal Pradesh India
Eligibility
Inclusion criteria
Inclusion criteria: lower distal uretric calculi of size less than or equal to 10 mm
Exclusion criteria
Exclusion criteria: 1.Patient not willing to give written informed consent. 2.Severe hydroureteronephrosis. 3.Multiple ureteric calculi. 4.Bilateral ureteric calculi. 5.Pregnancy. 6.Previous ureteric and bladder surgery. 7.Anatomical abnormalities of genitourinary tract. 8.Solitary functioning kidney. 9.Infective complications 10.Concurrent administration of diuretics and calcium channel blockers. 11.Patient allergic to study drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stone expulsion rate in lower ureteric stone of size less than or equal to 10mmTimepoint: After 4 weeks of treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)To compare the stone expulsion interval for medical expulsive therapy with silodosin & mirabegron. 2)Analgesic requirement in medical expulsive therapy with silodosin & mirabegron.Timepoint: After 4 weeks of treatment | — |
Countries
India
Contacts
Public ContactDr Ira Sharma
DR Rajendera Prasad Govermment Medical College Kangra at Tanda
Outcome results
None listed