Effect of types of analgesia on Diaphragm

The effect of intravenous patient control analgesia compared to patient control epidural analgesia on diaphragmatic excursion following abdominal surgery in adults: a prospective randomized control study.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/08/056970

Enrollment

Registered

2023-08-28

Start date

Unknown

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K319- Disease of stomach and duodenum, unspecified Health Condition 2: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere Health Condition 3: N29- Other disorders of kidney and ureter in diseases classified elsewhere Health Condition 4: K317- Polyp of stomach and duodenum

Interventions

Intervention1: Intervention: IVPCA-Intraoperative receive IV fentanyl at a 1-2 mcg/kg/hr. basal infusion. In ICU iv fentanyl will be given as a demand dose of 20 mcg fentanyl in 2ml and lockout interv

Eligibility

Inclusion criteria

Inclusion criteria: ASA I, II, and III adults aged 18 to 65 yrs undergoing major abdominal surgery.

Exclusion criteria

Exclusion criteria: Patient not willing to give consent, Difficult measuring diaphragmatic excursion preoperative area, psychiatry patient, contraindication for an epidural

Design outcomes

Primary

Measure	Time frame
To evaluate the effect of IVPCA on Diaphragmatic excursion as compared to PCEATimepoint: at 3hr post extubation.	—

Secondary

Measure	Time frame
Diaphragmatic excursion in both the groupsTimepoint: at 30 min & 24 hr following extubation or at shifting out of ICU. (Whichever is earlier);Diaphragmatic thickness fraction in both the groupsTimepoint: at 30 min, 3hr & 24 hr following extubation or at shifting out of ICU. (Whichever is earlier);Extubation failureTimepoint: within 72 hr;Resting pain & pain on movementTimepoint: at 30 min, 3hr, & 24 hr following extubation or at shifting out of ICU. (Whichever is earlier);Sedation (measured with RASSTimepoint: 30 min, 3hr, & 24 hr following extubation or at shifting out of ICU;Time to extubateTimepoint: from skin closure	—

Measure

Time frame

Diaphragmatic excursion in both the groupsTimepoint: at 30 min & 24 hr following extubation or at shifting out of ICU. (Whichever is earlier);Diaphragmatic thickness fraction in both the groupsTimepoint: at 30 min, 3hr & 24 hr following extubation or at shifting out of ICU. (Whichever is earlier);Extubation failureTimepoint: within 72 hr;Resting pain & pain on movementTimepoint: at 30 min, 3hr, & 24 hr following extubation or at shifting out of ICU. (Whichever is earlier);Sedation (measured with RASSTimepoint: 30 min, 3hr, & 24 hr following extubation or at shifting out of ICU;Time to extubateTimepoint: from skin closure

—

Countries

India

Contacts

Public ContactDr Alok Kumar Sahoo

All India institute of Medical Sciences

alokks108@gmail.com9438884160

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026