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Association of SPARC levels with the severity of coronary artery lesion in type 2 diabetic patients with coronary heart disease

Association of serum SPARC levels with the severity of coronary artery lesion in type 2 diabetic patients with coronary heart disease - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/08/056941
Enrollment
160
Registered
2023-08-25
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E115- Type 2 diabetes mellitus with circulatory complications

Interventions

Intervention1: Coronary angiography: The Gensini scoring system used an ordinal ranking based on stenosis severity in 11 coronary segments (score range, 0 to 72). Non-stenosed arteries were recorded w

Sponsors

FATHER MULLER RESEARCH CENTER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Above 18 years of age and either sex. 2. WHO diagnostic criteria of 1999 will be used for diagnosis of diabetes. 3.Diagnosis criteria of CAD

Exclusion criteria

Exclusion criteria: Post CABG and PCI cases, patients with severe liver and kidney dysfunction, hyperlipidemia, arthritis, previous previous history of myocardial infarction, post trauma and infection, cancer patients treated with chemo/radiation therapy.

Design outcomes

Primary

MeasureTime frame
It is hypothesized that if we can reduce SPARC content during the onset of T2DM, risk of CAD could be delayed. This study identifies the possibility of SPARC as a new early biomarker for diagnosing CAD in diabetic patients. This study may enable better life in patients diagnosed with diabetes and to deliver improved outcomes for diabetic patients when combined with clinical diagnostics.Timepoint: 8 months

Secondary

MeasureTime frame
In this study, the levels of serum SPARC & its association with the severity of coronary artery lesion in T2DM patients with CAD is assessed. QCA reports were also investigated by Gensini scoring to to explore quantitative analysis of coronary stenosis.Timepoint: 12 months

Countries

India

Contacts

Public ContactDr DIVIA PAUL ARICATT

Father Muller Medical College, Mangalore, Karnataka

drdiviamanoj@gmail.com08075789347

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026